Over the past six years, we have developed many DNA-based probes targeting a wide-range of bacteria that have been implicated in many deadly diseases. When this initiative first began, it was an academic theory exploring the boundaries of bioanalytical sciences. This ambition yielded novel molecular probes that have tremendous applications in healthcare and life sciences. The early, intuitive and cost-effective detection of infectious diseases is of utmost importance, especially in developing countries. Our research objective is to alleviate the current burden of pathogen detection through the development of affordable screening tests and simplified diagnostic strategies.